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No of entries selected: 9 of 711
1982
14 July
National Hemophilia Foundation
The National Hemophilia Foundation (USA) informs hemophilia patients and treating physicians about the 3 hemophiliac cases. They say that the CDC believes that the immune deficiency might be caused by a virus transmitted through blood or blood products, as is hepatitis, but that the risk of contracting this immunosuppressive agent was minimal.
Source: Krever Commission Report (1997), Vol 3, Part IV, Chap 27, page 742.
Type: Statement
Location: USA
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1982
9 December
National Hemophilia Foundation
The National Hemophilia Foundation informs its members that 4 new cases among US hemophiliacs have been identified, and stated that "while there is insufficient data to directly link the spread of AIDS to concentrates, there is an increased concern that AIDS may be transmitted through blood products."
"...patients and parents should be aware of the potential risks."
Source: Krever Commission Report (1997), Vol 3, Part IV, Chap. 27, page 769.
Type: Statement
Location: USA
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1983
May
1st US Product Withdrawal
The first factor VIII product withdrawal in the US occurs in May 1983. The National Hemophilia Foundation does not re-evaluate the use of factor concentrates.
Source: Krever Commission Report (1997), Vol 3, Part IV, Chap. 27, page 770.
Type: Development (Product Withdrawal)
Location: USA
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1983
late October
Cutter (& NHF Response)
Cutter orders a recall after being notified that a donor has died of AIDS in Texas. The donor died within 30 days of his last donation and the donor's plasma was used in numerous batches of Factor VIII and IX in the previous 2 years.

Note: In response to Cutter's product withdrawal, the National Hemophilia Foundation astonishingly advises patients to continue the use of concentrates or cryoprecipitate.

Source: Class Action Complaint (2004) Case No. C032572 PJH Page 31.
Additional Source: Krever Commission Report (1997), Vol 3, Part IV, Chap. 27, page 770.
Type: Product recall
Location: USA
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1984
January
Alpha product withdrawal
Alpha recalls its factor concentrates in January 1984. The National Hemophilia Foundation again reaffirm its recommendation that patients continue using concentrates or cryoprecipitate as prescribed by their physicians.
Source: Krever Commission Report (1997), Vol 3, Part IV, Chap. 27, page 770.
Type: Product withdrawal
Location: USA
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1984
April
National Hemophilia Foundation / CDC
The National Hemophilia Foundation learns that the CDC has received reports of 9 new cases of AIDS among US hemophiliacs in the first quarter of 1984. The National Hemophilia Foundation again fails to recommend any change in treatment.
Source: Krever Commission Report (1997), Vol 3, Part IV, Chap. 27, page 771.
Type: CDC Statistics
Location: USA
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1985
April
National Hemophilia Foundation - Recommends Against Recall
The National Hemophilia Foundation reverses its earlier recommendation for the recall of factor concentrates that may have been derived from a donor with AIDS.

Now that heat-treated factor concentrates are available, it recommends against recall because:

"HTLV-III [HIV] appears to be adequately killed under currently licensed heat treatment procedures."

Only non-heat-treated factor concentrates, it said, should be recalled.

The NHF now informs its members that heat-treated factor concentrates "may be the preferred products" for infants and children under 4 years of age with severe hemophilia and for newly identified hemophiliacs who have never been treated with factor concentrates.

Note: It has now taken 23 months for the National Hemophilia Foundation to revise its treatment recommendations regarding carrying on treating with concentrates despite the product recalls which began in May 1983. They now recommend physicians to alter treatment.

Source: Krever Commission Report (1997), Vol 3, Part IV, Chap. 27, page 758.
Additional Source: Krever Commission Report (1997), Vol 3, Part IV, Chap. 27, page 770-1.
Type: Decision Reversal
Location: USA
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1985
December
National Hemophilia Foundation
In December 1985, the National Hemophilia Foundation recommends that physicians prescribe only heat-treated concentrates for patients with severe hemophilia.
Source: Krever Commission Report (1997), Vol 3, Part IV, Chap. 27, page 771.
Type: Recommendation
Location: USA
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1993
National Hemophilia Foundation - Defendant in Class-Action
The National Hemophilia Foundation is the 5th defendant in the Chicago Class-action lawsuit on behalf of all U.S. hemophiliacs who acquired the AIDS or HIV from factor concentrates.

The National Hemophilia Foundation is said to have been too financially dependent on the plasma companies to have been an effective advocate for hemophiliacs. The foundation denies this, insisting that it believes the products' benefits outweigh the risks.

Source: FINAL Section: EDITORIAL REVIEW & OPINION Page: E01, SUNDAY April 16, 1995
Link #2
Type: Legal Action
Location: USA
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