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Magna Carta - 15th June, 1215

 
No of entries selected: 5 of 711
1982
13 September
UKHCDO - Dr Craske - Knowledge of US Haemophiliac AIDS Cases
In a Haemophilia Centre Directors' Organisation meeting in September 1982, there is not only knowledge of AIDS infecting haemophiliacs in the USA, but also, there is some understanding of the possible involvement of commercial blood products.

Dr Craske is tasked with looking into reports of the syndrome in 3 haemophiliacs from the United States. HCDO minutes state that: "It appeared that there was a remote possibility that commercial blood products had been involved."

Source: Link #1
Type: HCDO Minutes
Location: UK
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1983
15 January
Dr Jones - Link Between AIDS and Common Cell Immunity in Haemophiliacs
A Lancet report by Dr Jones describes the link between AIDS and common cell immunity in haemophiliacs.
Source: Haemophiliac HIV Litigation, Advice on Settlement Document, Appendix 1, Chronology, pp 56-58.
Type: Lancet Report
Location: UK
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1983
23 March
US Food and Drug Administration - Post-March 23rd Regulations
FDA requirements on blood donations introduced.
Source: Haemophiliac HIV Litigation, Advice on Settlement Document, Appendix 1, Chronology, pp 56-58.
Type: Regulations
Location: USA
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1983
13 May
DHSS - Inaction over AIDS - Decision not to Withdraw US Factor VIII
In a DHSS letter of 13th May 1983, it is clear that the DHSS has had sight of a letter from the CDSC (dated 9th May 1983), in which a recommendation that American FVIII concentrates should be withdrawn from use because of the risk of transmitting AIDS.

Nevertheless, the DHSS appear to take little notice:

"In my view this suggestion is premature in relation to the evidence and unbalanced in that it does not take into account the risks to haemophiliacs of withdrawing a major source of their FVIII supplies".

Note: Where were the DHSS obtaining their medical advice? The HCDO had already had 9 months to consider the problem of imported Factor VIII as Dr Craske had been specifically tasked by the HCDO with looking into reports of AIDS in 3 haemophiliacs from the United States - this was in September 1982. Dr Craske, at that time, had suspected a link to commercial Factor VIII and this was minuted.

Source: Additional Source: Minutes of the 13th Meeting of U.K. HCDO
Link #2
Type: Recovered Document - DHSS Letter. Med SEB. 'Action on Aids'. Dated 13th May 1983.
Location: UK
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1983
13 May
Haemophilia Reference Centre Directors - Decision Not to Restrict Imported Factor VIII
At a Meeting of the Haemophilia Reference Centre Directors on 13th May 1983, the Directors decided that, on the evidence available, (and because of the benefits of treatment), that no restriction should be placed on imported Factor VIII concentrate.

The only exception the Directors made was to continue with their policy of only using NHS material for children under the age of 4 and for mild haemophiliacs.

Background: Why didn't the Directors of Haemophilia Centres try and do more to ban imported Factor VIII concentrate? They appear to have ignored the following warnings:

  • Dr Craske had been tasked by the HCDO with looking into reports of the syndrome in 3 haemophiliacs from the United States a whole 9 months before (in September 1982) and he suspected a link to commercial Factor VIII.
  • 5 months earlier, (January 1983) there had been an article in the Lancet by Dr Jones (also HCDO), where AIDS was linked to common cell immunity in haemophiliacs.
  • The FDA requirements on blood donations had already been introduced on 23rd March 1983 - this was 2 months before this decision.
  • On 6th May, (1 week earlier) the CDSC telephoned the DHSS to inform them that a 23 year old haemophiliac patient in Cardiff was now showing symptoms of an AIDS diagnosis after having been infused with US Factor VIII.
  • On 9th May 1983, (4 days earlier), the CDSC had written a letter recommending that American FVIII should be withdrawn from use due to the risk of transmitting AIDS. The DHSS definitely had sight of this CDSC letter by 13th May 1983.
Source: Additional Source: Minutes of the 13th Meeting of U.K. HCDO
Link #2
Type: Recovered Document - AIDS Background Paper II. Dated 31st May 1983.
Location: UK
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